Before using Glucagon, tell your doctor about all of your medical conditions, including if you:

• have kidney problems
• have pancreas problems.
• have not had food or water for a long time (prolonged fasting or starvation).
• have low blood sugar that does not go away (chronic hypoglycemia).
• have heart problems.
• are pregnant or plan to become pregnant. It is not known if Glucagon will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if Glucagon passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Glucagon may affect the way other medicines work, and other medicines may affect how Glucagon works. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

When using Glucagon, you should:

• Read the detailed Instructions for Use that come with Glucagon.
• Use Glucagon exactly as your doctor tells you to.
• Make sure that you and your family know how to use Glucagon the right way before you need it.
• Act quickly. Having very low blood sugar for a period of time may be harmful.
• Call for emergency medical help right after you use Glucagon.
• If the person does not respond after 15 minutes, another dose may be given, if available.
• Eat sugar or a sugar sweetened product such as a regular soft drink or fruit juice as soon as you are able to swallow.
• Tell your doctor each time you use Glucagon. Your doctor may need to change the dose of your diabetes medicines.

Glucagon may cause serious side effects, including:

• High blood pressure. Glucagon can cause high blood pressure in certain people with tumors in their adrenal glands.
• Low blood sugar. Glucagon can cause low blood sugar in patients with tumors in their pancreas called insulinomas and Glucagonomas by making too much insulin in their bodies.
• Serious allergic reactions. Call your doctor or get medical help right away if you have a serious allergic reaction including: rash, difficulty breathing, or low blood pressure.

The most common side effects of Glucagon include:

• swelling at the injection site
• redness at the injection site
• vomiting
• nausea
• decreased blood pressure
• weakness

• headache
• dizziness
• pale skin
• diarrhea
• sleepiness or drowsiness

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Glucagon. Call your doctor for medical advice about side effects. You may report side effects to FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.

This Important Safety Information does not include all the information needed to use Glucagon for Injection safely and effectively. To learn more about Glucagon for Injection, talk to your doctor or pharmacist. Please see the full prescribing information for Glucagon for Injection and Patient Information. The full prescribing information is also available at www.fresenius-kabi.com/us.